From an excellent New Yorker article about the exoplanet detected in Proxima Centauri:
In the coming decades, we will discover exoplanets by the tens of thousands and will come to know them, from afar, in intimate detail. Yet the nearest one is an eighty-thousand-year drive away. Whatever Proxima b is like today—that is, 4.3 years ago—it’s likely to be vastly different eighty thousand years from now. In fact, it wouldn’t even be there by the time we arrived. Stars wander ever so slightly, and the cosmos as a whole is expanding; in the next eighty thousand years, Proxima Centauri and its planet will have moved two light-years farther from Earth, adding another forty thousand years to the trip.
Also, probably unrelated but I came across this Reinhold Niebuhr quote in my reading the other day:
The will-to-power uses reason as kings used courtiers and chaplins to add grace to their enterprise.